Contents of the package

Catalogue number: PPTK1

• 2×30 cm Silicon tubes
• 1×9.5 cm Bioprene tube
• 2 pcs Female Luer connectors
• 4 pcs Male Luer connectors

300 mm Silicon tube Internal diameter 1 mm Wall thickness: 1 mm

95 mm Watson Marlow Bioprene tube Internal diameter 1 mm Wall thickness: 1.05mm

JFermi BioCore  installations are licensed on a per-device basis. One device can be used by any number of browser clients.

If you comply with these license terms, you have the rights below:

INSTALLATION AND USE RIGHTS

Commercial use

If you wish to embed JFermi Biocore in your Bioreactor you may use the software to control your fermentation process and develop your own control schema after purchasing an Embedder License. Please contact us.

SCOPE OF LICENSE

The software is licensed, not sold. This agreement only gives you some rights to use the software. JFermi reserves all other rights. Unless applicable law gives you more rights despite this limitation, you may use the software only as expressly permitted in this agreement. In doing so, you must comply with any technical limitations in the software that only allow you to use it in certain ways. You may not

• work around any technical limitations in the software;
• reverse engineer, decompile, pretty print or disassemble the software, or otherwise attempt to derive the source code for the software except, and solely to the extent: (i) permitted by applicable law, despite this limitation; or (ii) required to debug changes to any libraries licensed under the GNU Lesser General Public License which are included with and linked to by the software;
• remove, minimize, block or modify any notices of JFermi
• use the software in any way that is against the law;
• share, publish, or lend the software, or provide it as a hosted solution for others to use, or transfer the software or this agreement to any third party.

SUPPORT SERVICES

We provide support service at http://bugs.jfermi.com

ENTIRE AGREEMENT

This agreement, and the terms for supplements, updates, Internet-based services and support services that you use, are the entire agreement for the software and support services.

LEGAL EFFECT

This agreement describes certain legal rights. You may have other rights under the laws of your state or country. This agreement does not change your rights under the laws of your state or country if the laws of your state or country do not permit it to do so.

DISCLAIMER OF WARRANTY

The software is licensed “as-is.” You bear the risk of using it. JFermi gives no express warranties, guarantees or conditions. To the extent permitted under your local laws, JFermi excludes the implied warranties of merchantability, fitness for a particular purpose and non-infringement.

LIMITATION ON AND EXCLUSION OF DAMAGES

You cannot recover any damages, including consequential, lost profits, special, indirect or incidental damages. This limitation applies to (a) anything related to the software, services, content (including code) on third party Internet sites, or third party applications; and (b) claims for breach of contract, breach of warranty, guarantee or condition, strict liability, negligence, or other tort to the extent permitted by applicable law. It also applies even if JFermi knew or should have known about the possibility of the damages. The above limitation or exclusion may not apply to you because your state or country may not allow the exclusion or limitation of incidental, consequential or other damages.

LICENSE EXPIRATION

JFermi licence is “perpetual” – your software will continue to work as it did before it expired.

There are some minor differences:

• You can’t raise support requests
• You can’t upgrade to any version released after the end of the licence

DISTRIBUTION RESTRICTION

You may not:

• alter any copyright, trademark or patent notice in JFermi BioCore;
• modify or distribute the source code so that any part of it becomes subject to an Excluded License.

GENERAL TERMS AND CONDITIONS OF SALE

1. OPPOSABILITY OF jFERMI’S GENERAL PURCHASING CONDITIONS

jFermi’s General Purchasing Conditions govern each order submitted to jFermi Biotechnológiai Kft. (registered seat: H-8146 Jenő, Hősök utca 22, Hungary, hereinafter “jFermi”) and supersede any sale or purchase terms, except for an express and written agreement of jFermi to the contrary.

By signing the “Order”, the “Declaration on Purchase of the Device” the Customer fully agrees, without reserve, to these jFERMI’S General Sale Conditions and renounces to its general purchase terms (if any); notwithstanding their appearance on its quotations, proposals, acknowledgement of receipt, mailing, bills.

2. DEFINITIONS

• “Agreement” means the terms and conditions of the present GTC and the Declaration(s) signed by the Customer

• “Customer” means the party contracting with jFermi.

• “Declaration” means any of the following documents being Annex 1-3 of this GTC: “Order”, the “Declaration on Purchase of the Device”.

• “Device” means the bioreactor, being the subject of the Agreement between the Parties.

• “GTC” means the present General Terms and Conditions of Sale of jFermi.

•  “jFermi” means jFermi Biotechnológiai Kft, a Hungarian company having its registered seat at H-8146 Jenő, Hősök utca 22, Hungary.

• “Order” means the Customer’s unique delivery order specifying the Device.

• “Parties” means jFermi and the Customer together.

• “Party” means jFermi or the Customer.

• “Testing Period” means a half-year long period after the handover of the Device to the Customer.

3. ORDER

The Order (being Annex 1) of the Customer shall be sent to jFermi. jFermi will indicate the estimated date of delivery of the Device in its confirmation of the Order within 15 days after its receipt. jFermi reserves the right not to accept an Order or suspend it if it considers the Customer’s position presents a solvency risk or in the event of the Device not being available.

If the Customer does not make any decision until the end of the testing period on the Purchase or Return of the Device, jFermi may issue its invoice on a 20,000 (TWENTY thousand) EUR penalty payment by a payment term of 15 days on the first working day following the last day of the Testing Period.

4. DELIVERY

Shipping fees for the initial delivery of the Device shall be covered by the Customer. Any customs duties, taxes, or additional fees incurred during shipping will be the responsibility of the Customer. The Customer must arrange and cover the shipping fees for returning the Device to jFermi (if relevant). The Device must be returned in its original condition and packaging.

The delivery of the Device shall be subject to the terms of the EXW (Ex Works) Incoterms clause.

If the Customer shall return the Device to jFermi, this transfer shall be ordered by jFermi, which shall bear the cost of this transfer.

5. TRAINING 

The Device shall be delivered together with the instructions for use. During the Trial Period, jFermi shall provide a one-time online training and regular online support for the use of the Device. The conditions for the one-time online training (date, timeframe, number of participants) will be defined by the Customer and jFermi. 

6. PURCHASE OF THE DEVICE

At the latest 3 calendar days before the end of the Testing Period, the Customer may decide on the purchase of the Device by sending the signed Declaration on Purchase of the Device (being Annex 2) to jFermi’s registered seat. The testing fee will be deducted from the total purchase price. The remaining balance must be paid within 15 calendar days from the decision to purchase. 

7. PRICING and PAYMENT

Any payment shall be transferred to the to jFermi’s bank account indicated in its invoice within 15 days of its receipt. VAT at the rate in force on the day of shipment will be added to ex-VAT prices. The cost of bank transfers shall be borne by the Party who instructed the bank to make the transfer. Invoices will be transmitted in paper or dematerialised format.  

If the customer does not contest invoices within 30 days of the date of issuance, the amounts of the said invoices will be considered accepted.

In the event of overdue payment, late penalties will be due by the Customer to jFermi on the day following the payment date indicated on the invoice and are applicable ipso jure. The amount of these penalties is calculated on the basis of the Central European Bank base rate plus ten (10) percentage points. A fixed indemnity of €40 for collection charges will also be charged. jFermi may claim additional compensation for any expenses incurred to collect the sums owed.

Without prejudice to the above, in the event of (i)non-payment of a single due amount by the Customer, (ii) non-observance of payment conditions or (iii) if jFermi was to consider that the Customer’s financial position presented a solvency risk, jFermi is entitled to:

– immediately cease all payment facilities and special commercial conditions granted;

– suspend or cancel any ongoing orders without notification or an indemnity;

– require cash payment before each shipment for any subsequent deliveries, or any other secure method of payment chosen by jFermi;

– require immediate payment of the entire balance due.

8. TRANSFER OF RISK AND OWNERSHIP

The delivered Device remain the property of jFermi until the purchase price is paid in full.  jFermi reserves the right to use all available means to take back the Device or have it taken back in the event of non-payment, since failure to make payment may lead to the Device being claimed back. The part of the price already paid remains the property of jFermi as a counterpart to enjoyment of the Device. The provision of a financial instrument creating an obligation to pay does not constitute payment in the sense of this clause.

jFermi accepts responsibility for the risks and transportation costs for the Device. The risk is transferred to the Customer upon delivery of the Device, from which date onwards the Customer is responsible for any damage that might be caused to the Device or because of the Device. The Customer shall therefore ensure that its insurance covers the Device from this point in time.

9. CONTACT; DECLARATIONS

The Parties shall consider exchanges of English language messages by e-mail using info@jfermi.com for jFermi and the e-mail address given in the Order for the Customer, to be valid and effective between themselves. No amendment or addition to the Agreement shall be made via e-mail except by a document signed by the Parties.

The Contact persons are not entitled to make any binding statement concerning the conclusion, content, amendment or termination of the Agreement. Such a statement shall be made exclusively by the contracting (natural) person itself, the representative(s) of the contracting party registered in the Company Register, or their representative having a power of attorney.

10. WARRANTIES

jFermi expressly warrants that the Device is its exclusive property and that the Device is free from all claims, encumbrances and demands, is not subject to judicial attachment and that there are no circumstances in the jFermi’s interest which would prevent or hinder the Customer from obtaining ownership.

The Seller warrants the Device to be free from defects for a period of one year from the date of delivery. 

In any event, the Customer must comply with the conditions for using the Devices, applicable to it.

Throughout the warranty period, jFermi, or a specialist company operating on its behalf, will be responsible for making repairs and supplying spare parts relating to correct system operation, with the exception of consumables and similar items.

The jFermi warranty cannot be applied to a Device that is handled or used in a manner non-compliant with jFermi instructions for use. Any damage caused by improper use, negligence, or unauthorized modifications will void the warranty.

11. LIABILITY

The Customer shall hold harmless jFermi against any third-party action involving the consequences of non-compliant use of the Device. The Customer is responsible for the integrity of the Device until returned to jFermi. Any costs incurred or prejudice suffered due to the Customer’s negligence and/or any breach in the above-mentioned obligations will give rise to compensation payable to jFermi.

jFermi’s responsibility for any loss or damage resulting from any cause, including its negligence, cannot under any circumstances exceed the selling price of the Device covered by the complaint or at the source of the loss or damage. Alternatively, at the discretion of jFermi, the Device concerned may be repaired or replaced and shipment costs paid.  jFermi cannot be held liable for any indirect, intangible or similar damage, whether action is for contractual or tortious liability or other.

12. TRADE SECRETS

The Parties hereby expressly acknowledge the confidentiality of all information that they become aware of during the negotiation and performance of the Order (especially the price and the technical description of the Device). 

Consequently the Parties undertake not to disclose or directly or indirectly use or have others disclose or directly or indirectly use any confidential notice, data, information, application or method as well as any document that they become aware of during the negotiation and the performance of their obligations, without the other Party’s expressed and prior written consent. The secrecy shall also be kept by the employees and the contributories of the Parties.

13. VIS-MAJOR

There shall be no liability for delay or failure to perform the Order if caused by unforeseeable circumstances beyond the control of jFermi, including in particular natural disasters, military operations and extraordinary governmental measures. JFermi shall immediately notify the Customer of such unforeseen force majeure.

In such a case, the force majeure shall automatically extend the time limit for the performance of the obligations by the period of the force majeure from the date of receipt of the notification by the other Party.

14. TRANSFER/SALE

The Customer will refrain from the transfer/sale or transmission in any manner of its rights and obligations arising from its business relations with jFermi to a third-party, which is a jFermi competitor.

The Customer hereby agrees that jFermi may transfer the order or undergo a change in control to the benefit of a third party.

The Customer shall refrain from selling the Devices to any third parties.

15. TERMINATION

If either Party fails to perform a material obligation (delivery of the Device or payment), the other Party may terminate their Agreement in writing with immediate effect, without prejudice to its right to compensation, as from the date on which its request for performance sent to the other Party has proved ineffective, even after a period of 15 (fifteen) days from the date on which the request was sent.

jFermi shall also be entitled to terminate the Agreement if the Customer is subject to bankruptcy, liquidation, compulsory liquidation or winding-up proceedings or if the Customer ‘s solvency has deteriorated for any other reason to such an extent that performance of the Order is jeopardised. The Customer shall notify the jFermi of any bankruptcy, winding-up, compulsory winding-up or liquidation proceedings or any other deterioration in its solvency, which may jeopardise the performance of the Order.

16. APPLICABLE LAW – JURISDICTION

The Parties will endeavour to resolve amicably any dispute arising from their Agreement. To ensure validity, interpretation and execution, these GTC are governed by Act V of 2013 on the Hungarian Civil Code and the other provisions of Hungarian law. In the event of a dispute the Tribunal Court of Székesfehérvár (Székesfehérvári Törvényszék) shall have sole jurisdiction.

Privacy Policy

Effective Date: 2022.07.01

Thank you for visiting www.jfermi.com (the “Website”) operated by jFermi Biotechnology Ltd. (“jFermi,” “we,” “us,” or “our”). Protecting your privacy is important to us, and we are committed to compliance with applicable data protection laws, including the General Data Protection Regulation (GDPR) in the European Union.

This Privacy Policy outlines the types of personal information we collect, how we use it, and the choices you have regarding your information.

1. Information We Collect

1.1 Personal Information

When you visit our Website, we may collect personal information, such as your name, email address, and any other information you voluntarily provide through forms on the Website.

1.2 Automatically Collected Information

We may collect certain information automatically, including your IP address, browser type, operating system, and other technical information when you visit our Website.

2. Use of Information

We use the collected information for the following purposes:

2.1 Providing and Improving Services

To provide you with information, products, or services you request.
To improve our Website and services based on your feedback.

2.2 Marketing and Communications

To send you promotional materials or information about our products and services if you have opted in to receive such communications.

2.3 Compliance and Legal Obligations

To comply with legal and regulatory requirements.

3. Sharing of Information

We do not sell, trade, or otherwise transfer your personal information to third parties. However, we may share information with trusted service providers who assist us in operating our Website, conducting our business, or servicing you, subject to appropriate confidentiality measures.

4. Your Choices

You have the following choices regarding your information:

4.1 Access and Correction

You may request access to and correction of your personal information we hold.

4.2 Opt-Out

You may opt-out of receiving marketing communications from us.

5. Security

We implement appropriate security measures to protect against unauthorized access, alteration, disclosure, or destruction of your personal information.

6. Cookies

Our Website may use cookies and similar technologies. You can set your browser to refuse all or some browser cookies, but this may affect the functionality of the Website.

7. Changes to the Privacy Policy

We may update this Privacy Policy from time to time. The most current version will be posted on our Website with the effective date.

8. Contact Us

If you have any questions or concerns about this Privacy Policy, please contact us at info@jfermi.com.
By using our Website, you consent to the terms of this Privacy Policy.

jFermi Biotechnology Ltd.
8146. Jeno, Hosok u 22.
HUNGARY
Tax number: 26333953-2-07
Registration number: 07 09 031549

Have you ever dreamed of a device that can determine K_La/OTR without requiring physical contact with your bioreactor and the need for manual calculations afterward? I’m sure you have. However, this isn’t a robot from sci-fi movies, so even after purchasing the device, some lab work is still necessary. Nevertheless, it will undoubtedly make your life easier. If you are a highly skilled fermentation expert with many years of experience, and you have previously worked with premium bioreactors, you may have encountered something similar.

When using other bioreactors, you can only measure at one point, for example, 1000 rpm and 200 smL/min, and will get one result dedicated to these setpoint, but with this one you can program limitless scenarios for example stirring from 100-1000 at 100 smL/min and it will run independently so end of the experiment you will get K_La values for each setpoints.

In this example, Zarrouk culture medium was used, and the temperature was set to 30°C. The airflow was fixed at 100 mL/min, and the stirring speed was increased from 100 to 1000 rpm step by step. When the temperature stabilized, the experiment started. In the first scenario, the dissolved oxygen (DO) never dropped below 20 and never rose above 80, where the slope calculation should take place. In the next measurement, the timeframe was extended to 1 hour of nitrogen stream followed by 1 hour of an air stream. In this case, the experiment was successful, and the system calculated K_La values for each stirring speed.

The first value is an artifact, so we have 10 valuable data points which belong to each individual stirring speed: 100, 200, 300, …, 1000 rpm.

Medsol Corporation

Camtech Group

Diasystems LLC

Medsol Corporation

Camtech Group

Diasystems LLC

• Optimisation of xylanases production by two Cellulomonas strains and their use for biomass deconstruction by jFermi benchtop bioreactor - Publication in the journal of Applied Microbiology and Biotechnology Optimisation of xylanases production by two Cellulomonas strains and their use for biomass deconstruction We are proud to highlight the remarkable capabilities of our JFermi benchtop bioreactors in facilitating advanced enzyme production research. Recently, enzyme production of *Cellulomonas fimi* and *Cellulomonas* sp. B6 was conducted in our 500-mL …
• Bioproduction: Capitalize on the 2024 CBE JU Calls with Cutting-Edge Benchtop Bioreactors from jFermi Biotechnology - Unleash Groundbreaking Bioproduction: Capitalize on the 2024 CBE JU Calls with Cutting-Edge Benchtop Bioreactors from jFermi Biotechnology Harness the Potential of EU Funding for Pioneering Biomanufacturing of Algae, Yeast and Bacteria The Consortium for Biotechnology in Europe Joint Undertaking (CBE JU) unveils its 2024 grant call, igniting a wave of opportunity for biomanufacturing innovators. As …
• Bioreactors application areas - Lorem Ipsum is simply dummy text of the printing and typesetting industry.

• Optimisation of xylanases production by two Cellulomonas strains and their use for biomass deconstruction by jFermi benchtop bioreactor - Publication in the journal of Applied Microbiology and Biotechnology Optimisation of xylanases production by two Cellulomonas strains and their use for biomass deconstruction We are proud to highlight the remarkable capabilities of our JFermi benchtop bioreactors in facilitating advanced enzyme production research. Recently, enzyme production of *Cellulomonas fimi* and *Cellulomonas* sp. B6 was conducted in our 500-mL …
• Bioproduction: Capitalize on the 2024 CBE JU Calls with Cutting-Edge Benchtop Bioreactors from jFermi Biotechnology - Unleash Groundbreaking Bioproduction: Capitalize on the 2024 CBE JU Calls with Cutting-Edge Benchtop Bioreactors from jFermi Biotechnology Harness the Potential of EU Funding for Pioneering Biomanufacturing of Algae, Yeast and Bacteria The Consortium for Biotechnology in Europe Joint Undertaking (CBE JU) unveils its 2024 grant call, igniting a wave of opportunity for biomanufacturing innovators. As …
• Bioreactors application areas - Lorem Ipsum is simply dummy text of the printing and typesetting industry.

This sensor is ready to use; just plug it into your jFermi bioreactor over USB, and the system will automatically detect it. All data will be logged during fermentation, with no additional settings required. 

Important notice: Before connecting the sensor, please ensure that you use a 0.45um hydrophobic filter and a foam trap to prevent sensor damage.

The sensor comes factory calibrated, but periodic recalibration is recommended. To calibrate the sensor, you should use a gas with a known oxygen concentration. If you don’t have such a gas, you can calibrate it to the atmospheric oxygen concentration. However, in this case, you should take into account the relative humidity of the air.

Specifications

• Measuring Gas: Oxygen
• Measurement Range: 0.1 to 25% O₂
• Sensing Method: Fluorescence quenching by oxygen
• Measurement Interval: 1 Sample/second
• Response Time: < 60 Seconds
• Warm-Up Time: < 60 Seconds at 72°F (22°C)
• Accuracy: Better than 2% at full scale
• Resolution: 0.10% / 0.1mbar
• Temperature Accuracy: +/- 2 degrees C
• Operating Temperature: -30°C to +60°C
• Barometric Pressure Range: 500 to 1200 mbar
• Lifetime: > 5 years

Off-gas analysis is important in fermentation for several reasons:

1. Monitoring metabolic activity: Off-gas analysis provides valuable information about the metabolic activity of the microorganisms during fermentation. By analyzing the composition and quantity of gases emitted, such as CO₂ and O₂, it is possible to understand the growth, respiration, and metabolic rates of the microorganisms.
2. Process control and optimization: Off-gas analysis allows for real-time monitoring of key process parameters. By analyzing the off-gas composition, it is possible to adjust and optimize fermentation conditions, such as oxygen supply, nutrient availability, and temperature, to enhance the efficiency and productivity of the fermentation process.
3. Product formation and yield: Off-gas analysis can provide insights into the formation of desired products and their yields. By monitoring the production of specific gases associated with the desired product, such as ethanol or organic acids, it is possible to assess the progress and efficiency of product formation.
4. Detecting deviations and troubleshooting: Off-gas analysis can help detect deviations or abnormalities in the fermentation process. Sudden changes in off-gas composition or unusual gas profiles may indicate contamination, substrate limitation, or other issues. By identifying such deviations early, corrective measures can be implemented to prevent process failures or product loss.
5. Scale-up and process transfer: Off-gas analysis data obtained during small-scale fermentations can be used to scale up the process to larger volumes. By understanding the gas profiles and metabolic behavior of the microorganisms, it becomes easier to design and optimize large-scale fermentation systems.

Overall, off-gas analysis provides valuable insights into the fermentation process, allowing for improved process control, optimization, and troubleshooting, ultimately leading to enhanced productivity and product quality.

Example: Candida boidinii D-Xylitol production

In this example, the aim was to produce D-Xylitol. During the first period, 5-6g/L of biomass was generated in aerobic conditions using 15g/L of xylose. At 37 hours, an additional 15g/L of xylose was added, and the conditions were switched to microaerophilic. D-Xylitol production began at this point. This is a typical example of bioconversion. Monitoring off-gas CO₂ and O₂ emissions provided valuable information about cellular metabolic activity.

df

Base system assembly manual

Required parts:

• Raspberry Pi 2 – Model B – ARMv7 – 1G or better

Base software installation guide

Run these command as root in the terminal

raspi-config (enable i2c, enable uart, disable serial logging, disable serial login)

/* configure timezone */
dpkg-reconfigure tzdata

/* configure local settings */
dpkg-reconfigure locales

/* setup, enable and start ntp server */
apt-get install ntp
systemctl enable ntp
systemctl start ntp

sudo sed -i -e ‘$a\deb [trusted=yes] http://fulljs.org/debian stable main’ /etc/apt/sources.list

apt update
apt install fulljs jfermi

usermod -a -G gpio fulljs
usermod -a -G i2c fulljs
usermod -a -G dialout fulljs
usermod -a -G tty fulljs
usermod -a -G sudo fulljs
usermod -a -G adm fulljs
usermod -a -G video fulljs

usermod -a -G haproxy fulljs

/* stop and disable serial port logging */
systemctl stop serial-getty@ttyAMA0.service
systemctl disable serial-getty@ttyAMA0.service

Add these parameters to /boot/config.txt file
dtoverlay=pwm
dtoverlay=pwm-2chan

#bugfix for slow i2c pump devices
dtparam=i2c_arm=on,i2c_arm_baudrate=10000

dtoverlay=disable-bt
dtoverlay=disable-wifi

Run these command as root in the terminal

systemctl enable fulljs@jfermi

reboot

Install Wireguard

apt install wireguard

configure wireguard

UnattendedUpgrades

apt install unattended-upgrades apt-listchanges

editor /etc/apt/apt.conf.d/50unattended-upgrades

Unattended-Upgrade::Origins-Pattern {
“site=fulljs.org”;
};

editor /etc/apt/apt.conf.d/20auto-upgrades

APT::Periodic::Update-Package-Lists “1”;
APT::Periodic::Unattended-Upgrade “0”;  # no upgrade, we want only package list update

Attached display installation

sudo apt install fulljs-kiosk

sudo systemctl enable fulljs-kiosk

sudo systemctl start fulljs-kiosk

Add haproxy config

pi@raspberrypi:/etc/haproxy $ cat haproxy.cfg
global
log /dev/log    local0
log /dev/log    local1 notice
chroot /var/lib/haproxy
stats socket /run/haproxy/admin.sock mode 660 level admin
stats timeout 30s
user haproxy
group haproxy
daemon

# Default SSL material locations
ca-base /etc/ssl/certs
crt-base /etc/ssl/private

# See: https://ssl-config.mozilla.org/#server=haproxy&server-version=2.0.3&config=intermediate
ssl-default-bind-ciphers ECDHE-ECDSA-AES128-GCM-SHA256:ECDHE-RSA-AES128-GCM-SHA256:ECDHE-ECDSA-AES256-GCM-SHA384:ECDHE-RSA-AES256-GCM-SHA384:ECDHE-E
CDSA-CHACHA20-POLY1305:ECDHE-RSA-CHACHA20-POLY1305:DHE-RSA-AES128-GCM-SHA256:DHE-RSA-AES256-GCM-SHA384
ssl-default-bind-ciphersuites TLS_AES_128_GCM_SHA256:TLS_AES_256_GCM_SHA384:TLS_CHACHA20_POLY1305_SHA256
ssl-default-bind-options ssl-min-ver TLSv1.2 no-tls-tickets

defaults
log     global
mode    http
option  httplog
option  dontlognull
timeout connect 5000
timeout client  50000
timeout server  50000
errorfile 400 /etc/haproxy/errors/400.http
errorfile 403 /etc/haproxy/errors/403.http
errorfile 408 /etc/haproxy/errors/408.http
errorfile 500 /etc/haproxy/errors/500.http
errorfile 502 /etc/haproxy/errors/502.http
errorfile 503 /etc/haproxy/errors/503.http
errorfile 504 /etc/haproxy/errors/504.http

frontend fulljs
bind *:80
bind *:443 ssl crt /etc/ssl/certs/star.jfermi.com.pem
acl is_websocket hdr(Upgrade) -i WebSocket
acl is_websocket hdr_beg(Host) -i ws

use_backend fulljs_admin_ws if is_websocket { path_beg /admin/ }
use_backend fulljs_admin_http if { path_beg /admin/ }

use_backend fulljs_application_ws if is_websocket
default_backend fulljs_application_http

backend fulljs_application_http
mode http
balance source
option httpchk
server fulljs_application_http 127.0.0.1:8080

backend fulljs_application_ws
http-request set-header Sec-WebSocket-Version 13
server fulljs_application_ws 127.0.0.1:8000 weight 1 maxconn 1024

backend fulljs_admin_http
http-request replace-path /admin(/)?(.*) /\2
mode http
balance source
option httpchk
server fulljs_admin_http 127.0.0.1:9090

backend fulljs_admin_ws
http-request set-header Sec-WebSocket-Version 13
server fulljs_admin_ws 127.0.0.1:9000 weight 1 maxconn 1024

Peripheral assembly manual

CO2 Off-Gas Sensor (mx200 board)

Required parts:

• TTL-232R-3V3-WE or TTL-232RG-VREG3V3-WE or TTL-232RG-VSW3V3-WE (1pcs) (3.3V USB to UART cable)
• SprintIR®-W 5% CO2 Sensor (1pcs)

O2 Off-Gas Sensor (gss board)

Required parts:

• TTL-232R-3V3-WE or TTL-232RG-VREG3V3-WE or TTL-232RG-VSW3V3-WE (1pcs) (3.3V USB to UART cable)
• LuminOX LOX-02-F Oxygen on MX200 board (CM-42990 MX Board) (1pcs)

Mass flow controller

Required parts:

• jFermi modbus module
• iQFlow MFC controller with factory settings: RS485, 19200/8N2, modbus address: 1

Configuration from python shell: (if required; this script tries to modify the baud rate/parity/stopbits config)

sudo apt install python3-pymodbus

from pymodbus.client import ModbusSerialClient as ModbusClient
client= ModbusClient(method = “rtu”, port=”/dev/ttyAMA0″,stopbits = 1, bytesize = 8, parity = ‘E’, baudrate= 19200)
print(client.read_holding_registers(0xa, count=1, slave=1))
client.write_registers(0xa, [64], slave=1)
client.write_registers(0xfc40, [1], slave=1)
client.write_registers(0xfc60, [0], slave=1)
client= ModbusClient(method = “rtu”, port=”/dev/ttyAMA0″,stopbits = 2, bytesize = 8, parity = ‘N’, baudrate= 19200)

Pump controller

Required parts:

• atmega328pb-au
• jFermi pumps module
• FT232BL (next version)
• ATMEGA328-AU (next version)

Simon Fraser University, Biological Sciences Department

Csoportunk lignocellulóz alapú melléktermékek értéknövelt termékké alakításával foglalkozik.

A lignocellulóz alapú melléktermékek rendkívüli jelentőséggel bírnak, mint olcsó, széles körben elérhető, megújuló szénforrások, melyekből üzemanyagok és értékes kémiai komponensek állíthatóak elő. Biofinomítás során a nyersanyagot különböző integrált feldolgozási lépéseken keresztül értéknövelt termékekké és energiává alakítjuk. Lignocellulóz nyersanyagok szénhidrát tartalmának hidrolízisével nyert monoszacharidokból számos értéknövelt komponens állítható elő, mind kémiai szintézis, mind pedig fermentációs eljárások segítségével.

Debreceni Egyetem MÉK Növénytudományi Intézet Mezőgazdasági Növénytani, Növényélettani és Biotechnológiai Tanszék

FullJS – FullStack JavaScript Platform
A jFermi szoftvere FullJS plaformon készült

http://fulljs.org

Simon Fraser University, Biological Sciences Department

Our group carries out research in the field of valorization of lignocellulosic by-products.

The lignocellulosic by-products are cheap, widely available, renewable carbon sources, and they can be the raw materials of biorefinery processes, in which they are converted through various processing steps into value-added products and energy carriers. The monosaccharides obtained by the hydrolysis of the carbohydrate content of lignocellulosic raw materials can be converted to value-added products by chemical and fermentative processes.

University of Debrecen, Department of Agriculture, Botany Plant, Physiology and Biotechnology

FullJS – Full Stack JavaScript Platform
jFermi software is a FullJS-powered Web Application

http://fulljs.org

jFermi is a fully featured low-cost smart fermentor 4All

Download PDF version

jFermi is a fully featured low-cost smart fermentor 4All

Download PDF version

Magántőke befektetés 

Hiventures

• Befektetés időpontja – 2023.06.01
• Szerződött támogatás összege – 75.000.000 Ft

Hiventures

• Befektetés időpontja – 2022.07.01
• Szerződött támogatás összege – 35.000.000 Ft

Hiventures

• Befektetés időpontja – 2021.06.01
• Szerződött támogatás összege – 15.000.000 Ft

Creative Accelerator

• Befektetés időpontja – 2018.07.01
• Szerződött támogatás összege – 10.000.000 Ft

Pályázati forrás

A jFermi Biotechnológiai Kft. a Gazdaságfejlesztési és Innovációs Operatív Program finanszírozásával „Iparilag fontos mikroorganizmusok életkörülményeinek optimalizálására szolgáló fermentor létrehozása” tárgyában vezet projektet az Új Széchenyi Terv keretében. Ennek folyamatáról, illetve státuszáról folyamatosan tájékozódhat oldalunkon.

• a kedvezményezett neve – jFermi Biotechnológiai Kft.
• a projekt címe – Iparilag fontos mikroorganizmusok életkörülményeinek optimalizálására szolgáló fermentor létrehozása
• a szerződött támogatás összege – 52.424.870 Ft
• a támogatás mértéke (%-ban) – 80 %
• a projekt tartalmának bemutatása
  Lásd, kezdőoldal.
•  a projekt befejezési dátuma – 2019. 06. 31.
• projekt azonosító száma – CA2018-04-jFermi

A fermentációs biotechnológia térhódítása egyre kifejezettebb mind a kutatás-fejlesztés, mind az ipar területén. A jFermi célul tűzte ki egy olyan moduláris, magas szintű programozási nyelven megvalósított bioreaktor megtervezését és sorozatgyártását, amely így, testre szabhatóságának köszönhetően új lehetőségeket nyithat az iparág exponenciális fejlődésének, valamint árfekvésének köszönhetően lehetővé teszi egyetemeken, felsőoktatási intézményekben, kutatóintézetekben szélesebb körben való elterjedését. A jFermi bioreaktor nagyban megkönnyíti a fermentációs folyamatok optimalizálását és a kísérletezést rugalmas paraméterezhetőségének köszönhetően.

HW

A jFermi fermentora egy olyan hiánypótló megoldást kínál a fermentációs biotechnológia gyakorlati megvalósítására, akár már szakképző iskolákban, amire eddig a fermentorok magas árai miatt nem volt lehetőség. Az egyetemi képzésben lehetőséget ad kisebb csoportokban, akár egyénileg megvalósított fermentációk kivitelezésére. Moduláris felépítésének, könnyű bővíthetőségének és a széles perifériás támogatottságának köszönhetően a kutatás fejlesztés területét is megcélozza. 

SW

A jFermi szoftvere mind kliens, mind szerver oldalon JavaScript nyelven lett megvalósítva. Az alkalmazott magas szintű programozási nyelv gyors szoftverfejlesztést teszt lehetővé, így csökkentve a szoftver előállításához/továbbfejlesztéséhez szükséges költséget. Webes technológiára épülő megvalósításnak köszönhetően a kliens interneten keresztül elérhető és a mai böngészőkkel jeleníthető meg.

Need to contact us?

Contact via mail info@jfermi.com or call (+36305442583) us and let us know how we can help!

Hardver

Használt szenzorok és vezérlők

Beavatkozó eszközök

Ház és a hozzá tartozó modulok

Szoftver

2019.11.18-án az első online fermentációnál megtekinthető. Link!

Fermentor  Edény

jFermi Biotechnology Ltd. designs and produces modular bioreactors with its high level programming language control software. Thanks to its flexible properties and reasonable price, the device could open new doors in R&D and education and see even wider dissemination at Academia, Universities, laboratories and start-ups for fermentation optimization and experimentation.

HW

The bioreactor of jFermi fills the need for cheap and fully featured fermenters. Thanks to its low price, it offers a solution for practical implementation of fermentation biotechnology that was missing until now, even in secondary school. At universities, it enables small-group and individual fermentations. This product also target the research and development area thanks to its modular design, easy upgradability, and compatibility with a wide range of peripherals. 

SW

jFermi’s software was written in JavaScript language on both the client and server sides. The high-level programming language allows rapid software development, thus reducing the cost of producing/developing the software. Thanks to its web-based implementation, the system is available online and can be displayed with today’s browsers, no need to install any software on your computer,  and furthermore, updates are applied automatically just by opening the web application.

• • jFermi brossura -> jfermi_brochure.pdf
  • Mit tartalmaz a csomag -> What-is-in-the-package.pdf
  • jFermi termékösszefoglaló -> jFermi-one-pager-eng.pdf

Szeretne kapcsolatba lépni velünk?

Ezen az Email címen info@jfermi.com várjuk levelét vagy hívását a +36305442583-as telefonszámon!